h120 and 793/b type vaccine strains combination protects chickens against challenge with qx like infectious bronchitis virus
نویسندگان
چکیده
avian infectious bronchitis (ib) is a widely distributed poultry disease that has huge economic impact on poultry industry. the continuous emergence of new ibv genotypes and lack of cross protection among different ibv genotypes have been an important challenge. the present study was done to evaluate protection caused by two different serotypes’ vaccines (massachusetts & 793/b) in order to evaluate protection against challenge with iranian qx like-virus. the results showed a protective ability of the used vaccination program. the h120-793/b vaccinated group obtained 81% protection. these results indicate that the h120 + 793/b vaccines could be helpful for the reduction of economic losses caused by newly evolving qx ibv variants.
منابع مشابه
Detection of the Chinese Genotype of Infectious Bronchitis Virus (QX-type) in Iran
Case Report: Recently a 20-day-old layer flock with mortality has been submitted to the PCR Lab. Infectious Bronchitis Virus (IBV) has been detected in the clinical samples. Results: A phylogenetic tree based on a partial S1 gene sequence showed Iranian IBV variant located in LX4-type cluster. This cluster include all QXIBV-type detected in China and European countries. The highest sequence hom...
متن کاملProtection of chickens against infectious bronchitis virus with a multivalent DNA vaccine and boosting with an inactivated vaccine
The protective efficacy of DNA plasmids encoding avian infectious bronchitis virus (IBV) S1, N, or M protein was investigated in chickens. Chickens were inoculated monovalently (with plasmid pVAX1-16S1, pVAX1-16M, or pVAX1-16N alone) or multivalently (combination of the three different plasmids, pVAX1-16S1/M/N). A prime-boost immunization protocol against IBV was developed. Chickens were immuni...
متن کاملS1 gene sequence analysis of infectious bronchitis virus vaccinal strains (H120 & H52) and their embryo-passaged derivatives
Avian infectious bronchitis is an acute and highly contagious disease that mainly causes respiratory symptoms in poultry. A number of serotypes and variants of the viral agent with poor cross-protection are the major problem to achieve desired immunity from vaccination. The S1 subunit of S glycoprotein (spike) is the major determinant of IBV so that a minor change in amino acid sequence of this...
متن کاملVaccination against infectious bronchitis virus: A continuous challenge.
Infectious bronchitis virus (IBV) is a significant respiratory pathogen of commercial poultry that causes millions of dollars in lost revenue worldwide each year. Even though the poultry industry extensively vaccinates against IBV, emergence of new serotypes and variants continually occur, making control of the disease difficult. Current mass application strategies for IBV vaccines are ineffici...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
iranian journal of virologyجلد ۹، شماره ۱، صفحات ۲۱-۲۵
کلمات کلیدی
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023